Clinical Application of EOS Imaging System: a scoping review protocol

Introduction:
The EOS imaging system was originally developed to perform imaging with regards to medical con-ditions such as scoliosis and anisomelia. However, recent research suggest that the modality has other clinical uses that may benefit patients via reduced radiation dose and thus, improved patient safety.

Inclusion criteria:
Clinical in-vivo studies in humans of all ages and covering all anatomical, physiological as well as pathological areas, which describe or test the clinical application of the EOS imaging system. This scoping review will consider all quantitative study designs including systematic reviews and meta-analyses. However, phantom studies and conference abstracts will be excluded.

Methods:
Databases that will be searched include Embase, MEDLINE, CINAHL Complete, Scopus, Cochrane Library, Academic Search Premier and OpenGrey. Secondary relevant material will be identified using citation searching (backwards and forwards) through Google Scholar of included studies. In addition, author searching will be applied when relevant.
Articles, published in 2003 and onwards, in English, Danish, Norwegian, Swedish, French and German will be included. Identified records will be screened by two independent reviewers. Data extraction will include study type and design, age of participants, anatomical/physiological region, pathology, clinical endpoint, outcome measures, sample size and clinical application. Data will be pre-sented in a tabular form and as a narrative summary.