TY - JOUR
T1 - Crystallization kinetics within a generic modeling framework
AU - Meisler, Kresten T.
AU - Solms, Nicolas von
AU - Gernaey, Krist V.
AU - Gani, Rafiqul
PY - 2014
Y1 - 2014
N2 - A new and extended version of a generic modeling framework for analysis and design of crystallization operations is presented. The new features of this framework are described, with focus on development, implementation, identification, and analysis of crystallization kinetic models. Issues related to the modeling of various kinetic phenomena like nucleation, growth, agglomeration, and breakage are discussed in terms of model forms, model parameters, their availability and/or estimation, and their selection and application for specific crystallization operational scenarios under study. The advantages of employing a well-structured model library for storage, use/reuse, and analysis of the kinetic models are highlighted. Examples illustrating the application of the modeling framework for kinetic model discrimination related to simulation of specific crystallization scenarios and for kinetic model parameter estimation are presented. A generic modeling framework with kinetic model identification tools for crystallization modeling is presented to study crystallization kinetics of various systems. The advantages of systematically exploring the kinetics of multiple systems and employing a model library are highlighted. Morris screening is applied for model analysis and a possible reduction is discussed. © 2014.
AB - A new and extended version of a generic modeling framework for analysis and design of crystallization operations is presented. The new features of this framework are described, with focus on development, implementation, identification, and analysis of crystallization kinetic models. Issues related to the modeling of various kinetic phenomena like nucleation, growth, agglomeration, and breakage are discussed in terms of model forms, model parameters, their availability and/or estimation, and their selection and application for specific crystallization operational scenarios under study. The advantages of employing a well-structured model library for storage, use/reuse, and analysis of the kinetic models are highlighted. Examples illustrating the application of the modeling framework for kinetic model discrimination related to simulation of specific crystallization scenarios and for kinetic model parameter estimation are presented. A generic modeling framework with kinetic model identification tools for crystallization modeling is presented to study crystallization kinetics of various systems. The advantages of systematically exploring the kinetics of multiple systems and employing a model library are highlighted. Morris screening is applied for model analysis and a possible reduction is discussed. © 2014.
KW - Crystallization
KW - Crystallization kinetics
KW - Crystallization operation framework
KW - Morris screening
UR - https://www.mendeley.com/catalogue/4429a286-633c-3a94-878f-94c4b1bf18b7/
U2 - https://doi.org/10.1002/ceat.201400044
DO - https://doi.org/10.1002/ceat.201400044
M3 - Journal article
VL - 37
SP - 1383
EP - 1392
JO - Chemical Engineering and Technology
JF - Chemical Engineering and Technology
SN - 0930-7516
IS - 8
ER -