Dimensional profiling of psychopathology in children and adolescents based on the K-SADS-PL and an analysis of the construct validity of two ADHD symptom dimensions

Julie Hagstrøm, Tine Nielsen, M Sørensen, K Aagaard, M Rasmussen, J Rosenberg, P Mohammadzadeh, A Sevelsted, N Hernández-Lorca, B Fagerlund, J Rydkjær, A Pagsberg, J Kaufmann, B Ebdrup, Niels Bilenberg, Jens Richardt Jepsen

Publikation: Bidrag til tidsskriftTidsskriftsartikelForskningpeer review

Abstract

Objectives
The traditional view on psychiatric disorders as categorical and distinct is being challenged by perspectives emphasizing the relevance of dimensional and transdiagnostic assessment. However, most diagnostic instruments are based on a categorical view with a threshold-approach to disease classification.

Methods
We here describe algorithms for dimensionalizing the psychopathological ratings of the widely used diagnostic interview for children and adolescents, the Kiddie-Schedule for Affective Disorders and Schizophrenia – Present and Lifetime Version (K-SADS-PL). We further evaluate the criterion-related construct validity of the dimensionalized attention-deficit/hyperactivity disorder (ADHD) scales using Rasch models in a sample of 590 children (mean age 10.29 (.36), 49% girls).

Results
The algorithms generate scores of current symptom load, i.e., the sum of clinician-rated symptoms within each disorder assessed with the interview. We found support for counting symptoms of inattention and hyperactivity/impulsivity, respectively, but not for a single combined ADHD scale.

Conclusions
The algorithms constitute an initial step in creating a framework for clinician-rated dimensional analyses of symptoms derived from the K-SADS-PL, but future studies are needed to further evaluate the construct validity of the remaining scales and the reliability and clinical utility of the method. We believe that our proposed algorithms offer a novel method of dimensional psychopathological assessment, which can be applied in multiple branches of child and adolescent psychiatry.
OriginalsprogEngelsk
TidsskriftNordic Journal of Psychiatry
Vol/bind78
Udgave nummer1
ISSN0803-9488
DOI
StatusUdgivet - 8 jan. 2024

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