DNA-selective hybridization and dual strand invasion of short double-stranded DNA using pyren-1-ylcarbonyl-functionalized 4'-C-piperazinomethyl-DNA.

Torsten Bryld; Torben René Højland; Jesper Wengel

doi:10.1039/B402414A

DNA-selective hybridization and dual strand invasion of short double-stranded DNA using pyren-1-ylcarbonyl-functionalized 4'-C-piperazinomethyl-DNA.

Torsten Bryld
, Torben René Højland
, Jesper Wengel

Syddansk Universitet

Publikation: Bidrag til tidsskrift › Tidsskriftsartikel › Forskning › peer review

Abstract

Incorporation of a novel pyren-1-ylcarbonyl-functionalized 4′-C-piperazinomethyl-DNA monomer into oligodeoxynucleotides leads to increased thermal stability of duplexes with DNA complements but reduced thermal stability of duplexes with RNA complements. This DNA-selective hybridization is explored for recognition of double-stranded DNA by a novel dual strand invasion approach

Originalsprog	Engelsk
Tidsskrift	Chemical Communications
ISSN	1359-7345
DOI	https://doi.org/10.1039/B402414A
Status	Udgivet - 2004
Udgivet eksternt	Ja

Adgang til dokumentet

10.1039/B402414A

Andre filer og links

https://portal.findresearcher.sdu.dk/en/publications/eccaf330-f19b-11db-821c-000ea68e967b

Citationsformater

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title = "DNA-selective hybridization and dual strand invasion of short double-stranded DNA using pyren-1-ylcarbonyl-functionalized 4'-C-piperazinomethyl-DNA.",

abstract = "Incorporation of a novel pyren-1-ylcarbonyl-functionalized 4′-C-piperazinomethyl-DNA monomer into oligodeoxynucleotides leads to increased thermal stability of duplexes with DNA complements but reduced thermal stability of duplexes with RNA complements. This DNA-selective hybridization is explored for recognition of double-stranded DNA by a novel dual strand invasion approach",

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doi = "10.1039/B402414A",

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journal = "Chemical Communications",

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T1 - DNA-selective hybridization and dual strand invasion of short double-stranded DNA using pyren-1-ylcarbonyl-functionalized 4'-C-piperazinomethyl-DNA.

AU - Bryld, Torsten

AU - Højland, Torben René

AU - Wengel, Jesper

PY - 2004

Y1 - 2004

N2 - Incorporation of a novel pyren-1-ylcarbonyl-functionalized 4′-C-piperazinomethyl-DNA monomer into oligodeoxynucleotides leads to increased thermal stability of duplexes with DNA complements but reduced thermal stability of duplexes with RNA complements. This DNA-selective hybridization is explored for recognition of double-stranded DNA by a novel dual strand invasion approach

AB - Incorporation of a novel pyren-1-ylcarbonyl-functionalized 4′-C-piperazinomethyl-DNA monomer into oligodeoxynucleotides leads to increased thermal stability of duplexes with DNA complements but reduced thermal stability of duplexes with RNA complements. This DNA-selective hybridization is explored for recognition of double-stranded DNA by a novel dual strand invasion approach

UR - https://portal.findresearcher.sdu.dk/en/publications/eccaf330-f19b-11db-821c-000ea68e967b

U2 - 10.1039/B402414A

DO - 10.1039/B402414A

M3 - Journal article

SN - 1359-7345

JO - Chemical Communications

JF - Chemical Communications

ER -