Endobronkial ultralyd-guided transbronchial finnåls aspiration: evaluering af bioanalytikeres præstationer ved rapid-on-site evaluering og preliminær diagnose

May Juhl Schacht, Cathrine Bønlykke Toustrup, Lene Bille Madsen, Marianne Schou Martiny, B B Larsen, J T Simonsen

Publikation: Bidrag til tidsskriftTidsskriftsartikelForskningpeer review

Abstract

Objectives: Rapid on-site evaluation (ROSE) of endobronchial ultrasound-guided transbronchial needle aspiration
(EBUS-TBNA) followed by a subsequent preliminary adequacy assessment and a preliminary diagnosis,
was performed at Aarhus University Hospital by biomedical scientists (BMS). The aim of this study was to
evaluate the BMS accuracy of ROSE adequacy assessment, the preliminary adequacy assessment and the
preliminary diagnosis as compared with the cytopathologist-rendered final adequacy assessment and final
diagnosis.
Methods: The BMS-rendered assessments for 717 sites from 319 consecutive patients over a 4-month period
were compared with the cytopathologist-rendered assessments.
Comparisons of adequacy and preliminary diagnoses were based on inter-observer Cohen’s Kappa coefficient
with a 95% confidence interval (CI).
Results: Strong correlations between ROSE and final adequacy assessments [Kappa coefficient of 0.90
(CI: 0.85–0.96)] and between the preliminary and final adequacy assessments [Kappa coefficient of 0.93
(CI: 0.87–0.99)] were found. As for the correlation between the preliminary and final diagnoses, the Kappa
coefficient was 0.99 (CI: 0.98–1).
Conclusion: Both ROSE and preliminary adequacy assessments as well as preliminary diagnoses, all
performed by BMS, were highly accurate when compared with the final assessment by the cytopathologist.
Bidragets oversatte titelEndobronkial ultralyd-guided transbronchial finnåls aspiration: evaluering af bioanalytikeres præstationer ved rapid-on-site evaluering og preliminær diagnose
OriginalsprogEngelsk
Artikelnummer10.1111/cyt.12338
TidsskriftCytopathology
Vol/bind27
Udgave nummer5
Sider (fra-til)344-350
Antal sider7
ISSN0956-5507
DOI
StatusUdgivet - 5 maj 2016
Udgivet eksterntJa

Emneord

  • Undersøgelsesdesign, teori og metode
  • Kliniske undersøgelsesmetoder, laboratorieteknologi og radiografi
  • Uddannelse, professioner og erhverv

Citationsformater