This study compares the effects of team-sport training, for sedentary men with lifestyle diseases, with fitness training in a pragmatic set-up in a community health centre (CHC). Thirty-two men in the fitness group (FiG) and 36 men in the team-sport group (TsG) completed the training and trained for 60–90 min, two times/week for 12–16 weeks. In FiG and TsG, mean heart rate (HR) during training was 73.2% and 74.5% of , respectively. Percentage of training time above 90% was 6 ± 9% and 10 ± 15% and the percentage of participants who spent > 10% of total training time with HR > 90% was 20% and 41%, in FiG and TsG, respectively. In FiG, total fat mass was reduced by 3.5% , while performance in the 6 min walking test (6MWT) increased by 11% . In TsG, total fat mass was reduced by 2.2% , while 6MWT performance improved by 5% . Between-group differences were observed for systolic BP and mean arterial pressure in favour of TsG and for sit-to-stand test in favour of FiG. In conclusion, small-sided team sport is a worthy alternative to fitness training since the overall health effects are comparable, for example, improved balance and reduced fat mass. Team sport elicits high heart rates and improves cardiovascular health by reducing blood pressure, while fitness training improves sit-to-stand test performance related to activity of daily living.