Miniaturization of a micro-optics array for highly sensitive and parallel detection on an injection moulded lab-on-a-chip

Tran Quang Hung; Yi Sun; Carl Esben Poulsen; Quyen Than Linh; Wai Hoe Chin; Dang Duong Bang; Anders Wolff

doi:10.1039/c5lc00176e

Miniaturization of a micro-optics array for highly sensitive and parallel detection on an injection moulded lab-on-a-chip

Tran Quang Hung
, Yi Sun
, Carl Esben Poulsen
, Quyen Than Linh
, Wai Hoe Chin
, Dang Duong Bang
, Anders Wolff

Danmarks Tekniske Universitet

Publikation: Bidrag til tidsskrift › Tidsskriftsartikel › Forskning › peer review

Abstract

A miniaturised array of supercritical angle fluorescence (SAF) micro-optics embedded in a microfluidic chamber was fabricated by injection moulding. The fabricated chip could enhance the fluorescence signal around 46 times compared to a conventional microscope. Collection of the fluorescence signal from the SAF array is almost independent of the numerical aperture, and the limit of detection was improved 36-fold using a simple and inexpensive optical detection system.

Originalsprog	Engelsk
Tidsskrift	Lab on a Chip
Vol/bind	15
Udgave nummer	11
Sider (fra-til)	2445-2451
Antal sider	7
ISSN	1473-0197
DOI	https://doi.org/10.1039/c5lc00176e
Status	Udgivet - 7 jun. 2015
Udgivet eksternt	Ja

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10.1039/c5lc00176e

C5LC00176EForlagets udgivne version, 3,24 MB

Citationsformater

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abstract = "A miniaturised array of supercritical angle fluorescence (SAF) micro-optics embedded in a microfluidic chamber was fabricated by injection moulding. The fabricated chip could enhance the fluorescence signal around 46 times compared to a conventional microscope. Collection of the fluorescence signal from the SAF array is almost independent of the numerical aperture, and the limit of detection was improved 36-fold using a simple and inexpensive optical detection system.",

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AU - Hung, Tran Quang

AU - Sun, Yi

AU - Poulsen, Carl Esben

AU - Than Linh, Quyen

AU - Chin, Wai Hoe

AU - Bang, Dang Duong

AU - Wolff, Anders

PY - 2015/6/7

Y1 - 2015/6/7

N2 - A miniaturised array of supercritical angle fluorescence (SAF) micro-optics embedded in a microfluidic chamber was fabricated by injection moulding. The fabricated chip could enhance the fluorescence signal around 46 times compared to a conventional microscope. Collection of the fluorescence signal from the SAF array is almost independent of the numerical aperture, and the limit of detection was improved 36-fold using a simple and inexpensive optical detection system.

AB - A miniaturised array of supercritical angle fluorescence (SAF) micro-optics embedded in a microfluidic chamber was fabricated by injection moulding. The fabricated chip could enhance the fluorescence signal around 46 times compared to a conventional microscope. Collection of the fluorescence signal from the SAF array is almost independent of the numerical aperture, and the limit of detection was improved 36-fold using a simple and inexpensive optical detection system.

U2 - 10.1039/c5lc00176e

DO - 10.1039/c5lc00176e

M3 - Journal article

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SN - 1473-0197

VL - 15

SP - 2445

EP - 2451

JO - Lab on a Chip

JF - Lab on a Chip

IS - 11

ER -

Miniaturization of a micro-optics array for highly sensitive and parallel detection on an injection moulded lab-on-a-chip

Abstract

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