TY - JOUR
T1 - Raising the Bar in the Diagnosis of Non-Small Cell Lung Cancer (NSCLC)
T2 - The Impact of Automated FISH Technology
AU - Zakariasen, Line Emilie Boje
AU - Fasting, Mary Mathilde Knoblauch
AU - Johnsen, Sys
AU - Teplaia, Svetlana
AU - Pedersen, Sanni Charlotte
AU - Necip, Filis Cramer
AU - Qvist, Camilla
PY - 2025
Y1 - 2025
N2 - The Met gene, which encodes a receptor tyrosine kinase, is crucial in cancer cell proliferation and survival. Fluorescence in situ hybridization (FISH) is vital for assessing MET-gene amplification in non-small cell lung cancer (NSCLC). Manual FISH assays are time-consuming and results are critical for treatment decision; automation could reduce turnaraound time. This study evaluates the potentional benefits of the automated FISH-system, Oncore Pro X (biocare Medical USA), by assessing factors including results, turnaround time, and cost.
AB - The Met gene, which encodes a receptor tyrosine kinase, is crucial in cancer cell proliferation and survival. Fluorescence in situ hybridization (FISH) is vital for assessing MET-gene amplification in non-small cell lung cancer (NSCLC). Manual FISH assays are time-consuming and results are critical for treatment decision; automation could reduce turnaraound time. This study evaluates the potentional benefits of the automated FISH-system, Oncore Pro X (biocare Medical USA), by assessing factors including results, turnaround time, and cost.
M3 - Journal article
SN - 2308-7706
VL - 14
SP - 24
EP - 38
JO - International Journal of Biomedical Laboratory Science
JF - International Journal of Biomedical Laboratory Science
IS - 1
ER -