The reproducibility of quantitative measurements in lumbar magnetic resonance imaging of children from the general population.

Youssef Masharawi, Per Kjaer, Tom Bendix, Claus Manniche, Niels Wedderkopp, Joan S Sorensen, N Peled, Tue Secher Jensen

Publikation: Bidrag til tidsskriftTidsskriftsartikelForskningpeer review


The anatomic configuration of the human spine has rarely been investigated in normal children yet commonly investigated in adults based on quantitative parameters of the motion segments (2 vertebrae and the disc in between). These parameters are usually measured directly from the vertebrae (defleshed from cadavers)1–10 or from diagnostic imaging [for example, radiographs, CT, or magnetic resonance imaging (MRI)].11–17 Recognizing the normal spinal shape and its development in children from the general population is important for early identification, prevention, and treatment of spinal pathologies both in children and adults (for example spondylolysis and scoliosis). In isthmic spondylolysis, for example, the unique anatomic configuration of the neural arch at L4 and L5 contributing to the development of the pars defect is well recognized in adults,18–21 yet remains obscure in children. Measuring the spine in children requires a reliable protocol as immature vertebrae may manifest irregular margins thus complicating their measurement procedure. This in turn may lead into unreliable results with false diagnostic and surgical conclusions.
TidsskriftSpine (Philadelphia, 1976)
StatusUdgivet - 2008
Udgivet eksterntJa