InTrans

    Project Details

    Description

    The increasing emergence and spread of antimicrobial resistance (AMR) determinants in the environment threatens humanity. Although tremendous effort has been devoted to short-term palliative measures such as AMR surveillance and the search for novel effective antimicrobials, the study of the dissemination of AMR, the cornerstone underlying this ominous health crisis, has been inadequately tackled and greatly overlooked.
    The aim of this project is to shed light on the transfer dynamics of AMR in the gastro-intestinal tract of humans, by coupling the most powerful technologies in the field with the most relevant model system available: human microbiota-associated (HMA) mice intestines.
    Our findings will present quantitative data on the extent of transfer and reveal which members of the microbiota take up AMR from ingested donor bacteria, altogether providing valuable insights that will help the design of alternative avenues for combating this health crisis.
    StatusFinished
    Effective start/end date01/10/1830/09/21

    Collaborative partners

    • University of Copenhagen (lead)
    • Technical University of Denmark

    Fingerprint

    Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.