Associations between adherence, depressive symptoms and health-related quality of life in young adults with cystic fibrosis

K. B. Knudsen, T. Pressler, Laust Hvas Mortensen, M. Jarden, M. Skov, A. L. Quittner, T. Katzenstein, K. A. Boisen

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Cystic fibrosis (CF) is a life shortening disease, however prognosis has improved and the adult population is growing. Most adults with cystic fibrosis live independent lives and balance the demands of work and family life with a significant treatment burden. The aim of this study was to examine the relationships among treatment adherence, symptoms of depression and health-related quality of life (HRQoL) in a population of young adults with CF. We administered three standardized questionnaires to 67 patients with CF aged 18–30 years; Morisky Medication Adherence Scale, Major Depression Inventory, and Cystic Fibrosis Questionnaire-Revised. There was a response rate of 77 % and a majority of the young adults (84 %) were employed or in an education program. Most participants (74 %) reported low adherence to medications. One third (32.8 %) of the participants reported symptoms of depression. HRQoL scores were especially low on Vitality and Treatment Burden, and symptoms of depression were associated with low HRQoL scores (p 
Original languageDanish
Article number1216
Issue number1
Publication statusPublished - 1 Dec 2016
Externally publishedYes

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