Cloning and sequencing of cDNAs specifying a novel class of phosphoribosyl diphosphate synthase in Arabidopsis thaliana

Britta N. Krath, Tina A. Eriksen, Tim S. Poulsen, Bjarne Hove-Jensen

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    Abstract

    cDNAs specifying four active phosphoribosyl diphosphate synthase isozymes were isolated from an Arabidopsis thaliana cDNA library. In contrast to other phosphoribosyl diphosphate synthases the activity of two of the A. thaliana isozymes are independent of Pi. Amino acid sequence comparison and phylogenetic analysis indicate that these two isozymes belong to a novel class of phosphoribosyl diphosphate synthases.
    Original languageEnglish
    JournalBiochimica et Biophysica Acta
    Volume1430
    Issue number2
    Pages (from-to)403-408
    ISSN0006-3002
    DOIs
    Publication statusPublished - 1999

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