TY - JOUR
T1 - Triplex-forming ability of modified oligonucleotides.
AU - Højland, Torben René
AU - Babu, Bolle Ravindra
AU - Bryld, Torsten
AU - Wengel, Jesper
PY - 2007/1/1
Y1 - 2007/1/1
N2 - We present our studies on the ability of several different nucleotide analogs as triplex-forming oligonucleotides. The modifications tested include 4'-C-hydroxymethyl, LNA, 2'-amino-LNA and N2'-functionalized 2'-amino-LNA. Triplexes containing monomers of N2'-glycyl-functionalized 2'-amino-LNA are particularly stable.
AB - We present our studies on the ability of several different nucleotide analogs as triplex-forming oligonucleotides. The modifications tested include 4'-C-hydroxymethyl, LNA, 2'-amino-LNA and N2'-functionalized 2'-amino-LNA. Triplexes containing monomers of N2'-glycyl-functionalized 2'-amino-LNA are particularly stable.
UR - https://portal.findresearcher.sdu.dk/en/publications/8e1fda20-e0ca-11dc-a57f-000ea68e967b
U2 - 10.1080/15257770701539047
DO - 10.1080/15257770701539047
M3 - Tidsskriftsartikel
C2 - 18066794
SN - 1525-7770
JO - Nucleosides, Nucleotides and Nucleic Acids
JF - Nucleosides, Nucleotides and Nucleic Acids
ER -